As a key feature of the face, fullness and definition of the lips are associated with attractiveness, sensuality, and youth. Similar to the skin, however, the lips are prone to intrinsic and extrinsic factors that can dramatically change their appearance over time.
Age-related thinning of this muscle, together with loss of support from the dentition of the upper jaw and volume loss from the body of the lip cause the upper white lip to lengthen and the red lip to fall vertically and take on a less averted, thinner appearance.
The Juvéderm® VOLBELLA® with Lidocaine study was designed to collect efficacy and safety data for volume enhancement and/or correction of asymmetry of the lips in normal subjects requesting aesthetic improvement.
The prospective, open label, multi-centre, post-marketing observational study of 62 subjects took place over 1 month, and was designed to evaluate the aesthetic impact of treatment with Juvéderm® VOLBELLA® with Lidocaine for volume enhancement or correction of asymmetry of the lips.
Aesthetic impact was evaluated by subject and physician immediately after injection and at the next follow-up visit (within 4 weeks post-treatment).
For the primary endpoint, 83.6% (n=51 out of 61) of subjects were at the first visit, ‘satisfied’, ‘very’ or ‘extremely’ satisfied with the improvement in their lips following treatment with Juvéderm® VOLBELLA® with Lidocaine.
Overall Juvéderm® VOLBELLA® with Lidocaine as a new treatment option for improvement of the lips was very well accepted by both subjects and physicians, associated with high levels of satisfaction and considered to result in a natural look and feel of the lips.